Guest Post | Advt. | Query:

Agilent Technologies Launches Updated Gene Expression Microarrays for Human, Mouse and Rat Models

Company Collaborates with Ghent University to Incorporate LNCipedia Content

SANTA CLARA, Calif., June 8, 2015

Agilent Technologies Inc. (NYSE: A) today announced updates to its SurePrint gene expression microarrays for messenger RNA profiling applications for human, mouse and rat models. The updates improve coding and noncoding content, which will provide up-to-date tools for researchers to investigate expression patterns on a highly accessible platform.

Agilent developed the updates to its flagship SurePrint G3 Human v3 gene expression microarray in collaboration with Ghent University for complete coverage of the LNCipedia 2.1 database to assay high-confidence, long noncoding RNA (lncRNA) transcripts.

LncRNAs (noncoding RNA longer than 200 nucleotides) modify gene regulation through direct interactions with DNA, RNA and proteins to enable target-specific or system-wide modulation. The broad but critical role of lncRNAs can be seen in their association with cancer, cardiovascular and neurodegenerative diseases.

Agilent’s redesigned gene expression microarrays are high-quality signature capture tools for efficient analysis of genes or pathways of interest with broad applications that range from aiding in disease stratification to elucidating drug mechanisms.

“We worked closely with Agilent to design a best-in-class profiling assay for mRNA and lncRNA expression,” said professor Jo Vandesompele of Ghent University. “Measuring both types of RNA in a single assay provides insight into the biological association between mRNA and lncRNA from relative expression levels. The key is having a good balance of coding and long noncoding features, and LNCipedia 2.1 is an optimal source to pair with Agilent’s gene expression content. The final microarray design is optimized and provides a lot of valuable information quickly.”

The updated microarrays are fabricated using SurePrint technology, which enables precision oligonucleotide synthesis. SurePrint microarrays have industry-leading sensitivity with greater than 5 logs of dynamic range, high reproducibility with an interarray median coefficient of variation of 5 percent, and excellent quantitative concordance with the External RNA Controls Consortium’s spike-in controls at R2>0.95.

“Our SurePrint gene expression microarrays encompass not only the rigor of expert content, such as LNCipedia’s lncRNAs, but also the flexibility of customization for expert users,” said Dr. Alessandro Borsatti, senior director of genomics at Agilent. “Through the high performance and quantitative concordance of our gene expression microarrays, along with our RNA-Seq and target-enrichment products, we enable researchers to smoothly transition between microarray screening applications and deeper next-generation sequencing discovery.”

SurePrint gene expression microarrays are part of the SurePrint product family, which includes microRNA and comparative genomic hybridization microarrays. Agilent’s genomic workflow includes the 2100 Bioanalyzer and 2200 Tapestation for quality control, SureScan scanner for data acquisition, GeneSpring software for data analysis, and the AriaMX system for real-time polymerase chain reactions.

Have any Question or Comment?

Leave a Reply

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.

…… ……. … …

……… …. …….

….. …… ………

……. ….. …….

.. ……. …….. 0

buy! buy! CHEAP! Telefonie VoIP CHEAP! buy! buy! CHEAP!

.. ……. …….. .

buy! buy! CHEAP! Telefonie VoIP CHEAP! buy! buy! CHEAP!


……. ….. ……..


For the 2012 MLB period, we found an totals forecast Joao’s Renowned Over/Under João Zorro Gonçalves, Zcode Totals Pro, System of the time with progressions that have been successful over 98 98% ... We eventually perfected our over/under program ( Zcodesystemexclusive ), although it h-AS has brought years of investigation. Five Steps to Making a Winning MLB Method: 1. Execute appropriate cash management tools. 2. MLB rules that are comprehend. 3.Extensive testing back to make sure successful longterm results ...


There is always a challenge when you're dealing with the Foreign Exchange Market. That's just the nature of the beast. The best thing you can do is to learn about how the market operates as a whole so that you will be ready to meet these challenges. iq option penipu Never be misled by any profit gains in binary options. This is the number-one way traders end up losing their money and ultimately failing. Remember that the same things that make you laugh can make you cry in this market, and you can lose that $700.



Learning Polish has never been this fun and easy as with our podcasts Learn Polish with Polishpod101 Start today and become conversational in Polish in no time


The Best Website Agen Poker Resmi Terpercaya come join


Do you need edmonton phone systems service ? Call complete communications today!

……… ……… .


High-tech solutions for easy start-up of your IPTV/OTT-business



If you want to purchase not only one item, you have a chance to enjoy privileges. There is a sale’ tab on the site which offers a fantastic range of reduced counterfeit watches and accessories, such as sunglasses, cufflinks, watch straps and pens. Luxury Jewelry Replica At MCA.MN On Sale You get a 5% discount if you buy two pieces, this discount increases to 10% if you buy 4 pieces or more. There is free international shipping on all orders on this site. We also offer customers a free return anytime with a 100% money back guarantee.